Ipsita Banerjee

PhD

Dr. Ipsita Banerjee

Associate Professor of Chemistry

Contact Information:
Email: banerjee@fordham.edu
Phone: 718-817-4445
Fax: 718-817-4432
Office: JMH 612

Professional Background

  • Nanotechnology/Biochemistry
  • BS University of Bombay
  • PhD University of Connecticut 

Research Interests:

Our goal is to explore and characterize nanoscale materials for studying cellular interactions and mimic biological assemblies by designing artificial biomaterials through molecular synthesis and nanoscale self-assembly for:

  • Tissue regeneration
  • Drug delivery
  • Tumor targeting
  • Bioimaging
  • Design of antibacterial materials
  • Tailored catalytic surface chemistry

Research Overview:

Our laboratory is interested in the study of molecular self-assembly and supramolecular nanostructures formed from various natural materials. The objective of this research is to  understand important fundamental aspects of the surface chemistry associated in the growth and development of such systems and investigate the effect of charge, surface stoichiometry, and binding interactions for the development of novel biomaterials and biosensors. For further improving the bone regeneration process, the design of biomaterials with surface properties similar to physiological bone would greatly enhance the formation of bone at the tissue/biomaterial interface and thus improve orthopaedic implant efficacy. We are working on development of new ceramic nanocomposites and examining their biocompatibility in vitro.

Overview of biomedical nanotechnology

Green Synthetic Methods for preparation of Nanoparticles
In recent times, biological methods to synthesize metal nanoparticles through environmentally friendly methods is becoming increasingly important. Using a biological approach via specific peptide sequences or modified plant based materials, we are examining the growth of highly crystalline shape and size controlled metal and semi-conductor nanoparticles. It is well known that the shapes and sizes of the nanoparticles play an extremely important role in the properties of the nanoparticles for the development of devices for optoelectronics, biosensors and imaging.

Nanoparticles can assemble into crystal-like arrangements
SEM images of quasi-crystalline nanomaterials
Seemingly amorphous nanomaterials can exhibit crystalline characteristics

Catalysis and Sensors
We are studying the growth of semiconducting nanoparticles such as tinoxide under mild conditions in the presence of proteins  to control the size and shape of the nanoparticles. We have recently grown nanoparticles of about 5 -10 nm in diameter. Such materials can be used in a range of applications that include gas sensing and catalysis. Investigating new bioengineering routes for the preparation of metal oxide nanoparticles and porous materials.  The aim  of this research is to develop new materials with tailored properties where in the shape, size, porosity and BET surface area can be controlled.

Nano scale structure and function

Protein Folding Dynamics at Biomimetic Surfaces
Misfolding of peptides are responsible for denaturation and accumulation of amyloid deposits leading to diseases such as dementia Alzheimer's and Parkinson's. We are studying the peptide folding dynamics of several related peptides at surfaces in order to shed light into the mechanism of formation of fibrillar tangles and their unfolding.